Trajenta Duo 2.5/500 Mg (Linagliptin/Metformin)

Introduction About TRAJENTA DUO 2.5/500MG TABLET

TRAJENTA DUO 2.5/500MG TABLET is a combination medicine (Metformin and Linagliptin) used to manage type II diabetes mellitus among adult patients when diet, exercise and management with other conventional medicines does not result in adequate sugar control. It is used as an adjunct therapy along with proper diet and exercise to achieve better results.

Take TRAJENTA DUO 2.5/500MG TABLET preferably with meals. During therapy with TRAJENTA DUO 2.5/500MG TABLET, your doctor might regularly monitor your blood sugar levels and kidney function to avoid the risk of unwanted side effects. Before taking TRAJENTA DUO 2.5/500MG TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have problems in blood circulation or are severely dehydrated due to excessive vomiting or diarrhea recently.

TRAJENTA DUO 2.5/500MG TABLET is not recommended for use in patients with severe uncontrollable diabetes. It is also not suitable for use in patients with alcoholism and in patients with severe systemic infections. Consult your doctor before taking TRAJENTA DUO 2.5/500MG TABLET if you are pregnant or breastfeeding. The most common side effects of taking TRAJENTA DUO 2.5/500MG TABLET are nausea, diarrhea, stomach pain, constipation, loss of appetite and metallic taste. Consult your doctor if any of these side effects trouble you.

Uses Of TRAJENTA DUO 2.5/500MG TABLET

• Type II diabetes mellitus

Benefits of TRAJENTA DUO 2.5/500MG TABLET in Type II diabetes mellitus:

Improved Blood Sugar Control

TRAJENTA DUO 2.5/500MG TABLET works by reducing glucose production in the liver and improving insulin sensitivity. It also helps increase insulin secretion in response to meals, effectively lowering blood sugar levels.

Reduced Risk of Hypoglycemia

Because TRAJENTA DUO 2.5/500MG TABLET does not cause significant insulin release in the absence of food, the risk of low blood sugar (hypoglycemia) is lower compared to other diabetes medications.

Weight Neutrality

The Metformin present in the medicine often helps in weight management, and linagliptin present in the medicine typically has a neutral effect on weight, making this combination a better choice for individuals concerned about weight gain.

Cardiovascular Benefits

Linagliptin has shown to have potential cardiovascular protective benefits, which can be important for diabetic patients who are at an increased risk for heart-related issues.

How TRAJENTA DUO 2.5/500MG TABLET Works

TRAJENTA DUO 2.5/500MG TABLET is an antidiabetic medicine. It contains two medicines namely Metformin and Linagliptin. Metformin makes the body more sensitive to insulin (a hormone involved in glucose metabolism). This helps our body cells to utilize more amount of the circulating blood glucose. Additionally, it can stop glucose production by the liver and reduces its absoprtion in the body. Linagliptin controls blood sugar levels by blocking the actions of an enzyme called dipeptidyl peptidase (DPP)-4 that reduces insulin secretion in the body. Collectively, TRAJENTA DUO 2.5/500MG TABLET controls blood sugar levels and improve glycemic control in patients with type II diabetes.

How to use TRAJENTA DUO 2.5/500MG TABLET

Take TRAJENTA DUO 2.5/500MG TABLET preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

Dosage and Administration

• The typical dosage is one tablet twice daily.
• It is usually taken with meals to minimize gastrointestinal side effects like nausea and diarrhea caused by metformin.
• Consistency is key: Take it at the same time daily to maintain steady blood sugar levels.
• Always follow your healthcare provider’s instructions.
• Your doctor may adjust the dosage based on your blood sugar levels, kidney function, and tolerance.

Missed Dosage instructions for TRAJENTA DUO 2.5/500MG TABLET

• If you forgot to take a dose, take it as soon as you remember.
• If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
• Do not double the dose to make up for the missed one, as this can increase the risk of side effects.

Overdosage instructions for TRAJENTA DUO 2.5/500MG TABLET

• Symptoms of overdose may include severe hypoglycemia (low blood sugar): Symptoms like dizziness, sweating, confusion, or fainting.
• Lactic acidosis (symptoms like muscle pain, difficulty breathing, fatigue, or abdominal discomfort)
• In such cases, seek immediate medical attention.

Side Effects Of TRAJENTA DUO 2.5/500MG TABLET

Like all medicines, TRAJENTA DUO 2.5/500MG TABLET may cause certain side effects, although not everybody gets them.

The most common side effects of taking TRAJENTA DUO 2.5/500MG TABLET are:

• Nausea and vomiting
• diarrhea, stomach pain
• changes in taste (metallic taste)
• increased lipase levels in blood
• Hypoglycemia

When to consult your doctor?

signs of severe decrease in blood sugar levels (such as increased sweating, feeling shaky, anxiety, blurred vision, tingling sensation in the lips, pale skin, mood changes or confusion)

serious allergic reaction (such as hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing)

severe skin rashes with redness and blistering of the skin

signs of lactic acidosis (cold hands or feet, dizziness or light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness or drowsiness, stomach pains, nausea or vomiting)

signs of liver damage (such as tiredness, loss of appetite, weight loss, with or without yellowing of the skin or whites of the eyes)

inflammation of the pancreas causing severe persistent stomach pain which radiates towards your back along with nausea and vomiting

How To Manage Side Effects